HEPATITIS C NEWS
- Virus C Hepatitis and Type 2 Diabetes: A Cohort Study in Southern Italy.
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- Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: A longitudinal analysis.
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- Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C
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- Gilead Submits New Drug Application to U.S. FDA For Sofosbuvir for the Treatment of Hepatitis C
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- As many as one in 50 people around the world is infected with some type of hepacivirus or pegivirus,
including up to 200 million with hepatitis C virus (HCV), a leading cause of liver failure and liver cancer.
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- AMSTERDAM ‐‐ Two years after direct‐acting antiviral drugs for hepatitis C virus (HCV) infection hit the
U.S. market, anemia has been far and away their most significant adverse effect, researchers said
here.
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- AMSTERDAM, the Netherlands — A regimen of 3 direct-acting antiviral drugs plus ritonavir and
ribavirin produced sustained virologic response rates in more than 90% of a broad range of patients
infected with hepatitis C 24 weeks after therapy, results from a new clinical trial show.
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- Gilead Submits New Drug Application to U.S. Fda for Sofosbuvir for the Treatment Of Hepatitis C
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- Sustained Virological Response Linked With Improved Survival for HCV Patients
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- Adherence to hepatitis C treatment: unraveling the complexities
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- HCV Treatment Pipeline Update
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- The Hepatitis‐Fibromyalgia Connection
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- Serious and Fatal Skin Reactions to Incivek
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- Triple therapy has poor safety in cirrhotic hepatitis C
BOSTON – In patients with chronic hepatitis C virus infections and compensated cirrhosis, a combination of a direct-acting antiviral agent, pegylated interferon, and ribavirin produced high on-treatment virologic response rates ...
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- Hepatitis C Reaching Crisis Levels; Requires Coverage for Routine Screenings
WASHINGTON, Nov. 27, 2012 -- Summit on HIV and Viral Hepatitis Charts Priorities to Accelerate Testing, Reduce Disparities in Care
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- Abbott Announces Phase 3 Hepatitis C Program Details
Abbott today released details on its phase 3 hepatitis C registrational program following promising results from its phase 2b clinical trial, known as Aviator, presented at the Annual Meeting of the American Association for the Study of Liver Disease (AASLD) in Boston.
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- HCV Drug Combo Promising All on Its Own
A three-drug regimen that eliminated both standard hepatitis C drugs has yielded positive early results in hard-to-treat patients, a researcher reported.
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- Simple HCV Regimen shows Promise
A simplified hepatitis C (HCV) regimen with just two oral drugs had promising results in a difficult-to-treat population, a researcher reported here.
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- Gilead posts positive results in mid-stage Hepatitis C study
(Reuters) - Gilead Sciences Inc on Saturday reported a 100 percent cure rate using a combination of drugs in a small number of patients with the most common and hardest to treat form of hepatitis C.
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- Abbott hepatitis C drugs bring high cure rates in trial
(Reuters) - A trio of oral medicines from Abbott Laboratories Inc to treat hepatitis C produced unprecedented cure rates in patients who had failed to benefit from standard treatment, as well as very high cure rates for newly treated patients, Abbott said on Saturday.
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- Washington Post Hepatitis & Liver Health Publication
National media coverage is finally happening. Read the articles in this publication for concise information about hepatitis C, CDC recommendations that all baby boomers get tested and much more.
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- ATTAIN Study
Clinical research doctors are looking for people with hepatitis C to participate in a clinical research study.
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- CDC Now Recommends All Baby Boomers Receive One-Time Hepatitis C Test
New approach will help avert major increases in liver disease and deaths in the U.S.
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- DDW: Hepatitis Patients at Risk for Accidental Acetaminophen Toxicity
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- Herbal & Dietary Supplements
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- Drug Interactions with Hepatitis C Virus NS3/4A Protease Inhibitors and HIV Medications: A Quick Guide for Clinicians
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- Telaprevir May Cause Severe Cutaneous Eruptions
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- EASL: Telaprevir and Boceprevir Effective but Cause Serious Side Effects in Patients With Cirrhosis
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- EASL: Interferon Lambda as Effective as Alfa for Hepatitis C but with Much Better Safety Profile
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- EASL: GS‐7977, Daclatasvir, and Asunaprevir Look Good in Interferon‐Free Regimens for Hepatitis C
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- Pancreatitis Forces Halt to HCV Drug Trial
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- High Cost of Telaprevir Overshadows Clinical Benefits in Patient Subset
Results Based on Cost-Effectiveness Model
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- Updated AASLD HCV Guideline Aims To Simplify Use of DAAs:
More Data Needed To Fill Gaps in Understanding
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- FDA Update Statin Labels Updated: HCV Protease Inhibitor Contraindication Highlighted
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- Federal Guidelines for the Treatment of Hepatitis C and Cirrhosis in Prisons 2012
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- The Cost-Effectiveness of Birth-Cohort Screening for Hepatitis C
Antibody in U.S. Primary Care Settings
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- Treatment of patients with chronic Hepatitis C Virus (HCV) infection with an interferon-free regimen
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- An Update on Treatment of Genotype 1 Chronic Hepatitis C Virus Infection: 2011 Practice Guideline by the American Association for the Study of Liver Diseases
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- HCV Protease Inhibitor Danoprevir Promising in Early Trial
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- DDW: Study Backs HCV Screens for All Boomers
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- Telemedicine Puts HCV Care in Hands of PCPs
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- Telaprevir (Incivek) Approved
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- BOCEPREVIR APPROVED
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- 4-Drug Combo with Telaprevir and VX-222 Clears HCV at 12 Weeks
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- First Sustained Response Data for Polymerase Inhibitor Mericitabine EASL
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- Pegylated Interferon Lambda Boosts Response with Few Side Effects EASL
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- Boceprevir Helps Hepatitis C Patients with Cirrhosis EASL
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- Statin Boosts Response to Pegylated Interferon/Ribavirin EASL
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- Liver Cancer in Cirrhotic Patients Effectively Treated With Radiofrequency Ablation, Study Suggests
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- HCV Infection and the Incidence of CKD
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- CDC Analysis Recommends Enhanced Acute Hepatitis C Surveillance
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- Clinical Virology Results from Telaprevir Phase 3 Study ADVANCE
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- Non response to peginterferon alfa and ribavirin in IL28B CC & CT patients can be overcome by high dose continuous interferon alfa-2b administration in combination with ribavirin for chronic hepatitis C
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- GI-5005 Therapeutic Vaccine Plus Peg-IFN/Ribavirin Improves Sustained Virologic Response Versus Peg-IFN/Ribavirin In Prior Non-Responders With Genotype 1 Chronic HCV Infection
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- Telaprevir in Combination with Peginterferon Alfa2a and Ribavirin for 24 or 48 weeks in Treatment-Naïve Genotype 1 HCV Patients who Achieved an Extended Rapid Viral Response: Final Results of Phase 3 ILLUMINATE Study
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- Response-Guided Therapy (RGT) with Boceprevir (BOC) + Peginterferon alfa-2b/Ribavirin (P/R) for Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype (G) 1 Was Similar to a 48-Wk Fixed-Duration Regimen with BOC + P/R in SPRINT-2
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- Completely individualized treatment durations with peginterferon-alfa-2b and ribavirin in HCV genotype 1-infected patients and importance of IL28B genotype (INDIV-2 study)
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- Long-term Follow-up of Patients with Chronic Hepatitis C Treated with Telaprevir in Combination with Peginterferon Alfa-2a and Ribavirin: Interim Analysis of the EXTEND Study
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- Maintenance peginterferon (pegIFN) therapy to prevent hepatocellular carcinoma (HCC) in patients with advanced chronic hepatitis C: extended follow - up results from the HALT - C Trial
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- FDA Issues Guidance for Development of Directing-acting Antiviral Drugs for Hepatitis C
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- Highest Rates of Hepatitis C Virus Transmission Found in Egypt
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- Vertex hep C drug works on many in 24 weeks: Study
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- KERRY & HONDA: Disrupting a deadly disease
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- Hispanics And Asians Less Likely To Receive Liver Transplants
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- FDA Approves Rapid Test for Antibodies to Hepatitis C Virus
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- Vitamin A and Treatment
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- Efforts to Up Minority Organ Donations Show Success
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- Study Finds Beta Blockers Alone More Effective for First Variceal Bleeding
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- Antiviral Therapy during Compensated Cirrhosis Most Cost-Effective Approach Treatment
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- Study Finds Poor Compliance with Cirrhosis Surveillance Recommendations Less than 20% of Qualified Patients Are Regularly Monitored
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- Peginterferon alfa-2B and Ribavirin for Liver Transplant Patients Yields 30% HCV SVR
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- Modest" Results With Nitazoxanide for HCV Genotype 1 Nonresponders
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- Study Links Liver Transplantation to Accelerated Cellular Aging
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- FDA Considers Expanded Use of HCV Drugs
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- Liver Donations from Living Donors Increase 42% after Educational Intervention
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- Infectious Disease Screening
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- Telaprevir Raises Response Rates in Hepatitis C
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- HCV Polymerase Inhibitor VX-222 Demonstrates Good Safety and Antiviral Activity in Treatment-naive Genotype 1 Hepatitis C Patients
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- HCV Protease Inhibitor Danoprevir (RG7227/ITMN-191) Shows Antiviral Activity at Lower Doses When Boosted with Ritonavir
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- HCV Protease Inhibitor Boceprevir Demonstrates Durable Sustained Response with No Late Relapse
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- Vertex Will Study All-Oral Regimen of HCV Protease Inhibitor Telaprevir plus Polymerase Inhibitor VX-222
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- U.S. Doctors Sanction Transplant Criteria for Liver Cancer Patients
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- Vertex Broadens its Commitment to Improving HCV Care with Clinical Trial to Evaluate Combination Regimens Based on Oral Antiviral Therapies
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- Is One Type of Pegylated Interferon More Effective for Treating Chronic Hepatitis C?
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- Hepatitis and Liver Cancer: A National Strategy for
Prevention and Control of Hepatitis B and C
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- Liver Donations from Living Donors Increase 42% after Educational Intervention
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- Vaccines May Lower Viral Load Improve Treatment Response
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- African Americans Fare Worse After Undergoing Liver Transplantation Due to Hepatitis C
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- Metabolic Factors That Predict Rapid Virologic Response to Peginterferon/Ribavirin in HCV Patients
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- Weight Loss: A Modifiable Lifestyle Parameter That Can Alter HCV Liver Disease Progression
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- Silent Epidemic of Viral Hepatitis May Lead to Boom in Serious Liver Disease
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- Direct Antivirals Can Beat HCV Without Interferon
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- HCV Response Linked Strongly to Gene Variant
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- Schering-Plough Reports Potent Antiviral Activity With Narlaprevir (SCH 900518), An Investigational, Once-Daily Protease Inhibitor For Hepatitis C
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- More Than 80 Percent Of HCV Genotype 1 Treatment-Naive Patients Achieved Sustained Virologic Response With Twice-Daily Telaprevir-Based Regimen
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- Sprint 1 Study, Phase 2, Boceprevir
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- Pegylated Interferon Lambda Demonstrates Good Antiviral Activity, May Cause Fewer Side Effects than Interferon Alfa
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- Coffee Could Stall Liver Disease Progression
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- Hepatitis C Drug Development at a Crossroads - Comments from the Editors
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- Hypertension and Diabetes Are Concern in Long-Term Care of Liver Transplant Patients
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- The FDA has just issued new warnings in the package inserts for alpha interferons
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- Women, Blacks, Medicare Recipients Less Likely To Be Evaluated For Liver Transplantation
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- New Biomarker Predicts Response to Hepatitis C Treatment
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- Protein & Cholesterol May Increase Risk Of Cirrhosis & Hepatocellular Carcinoima
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- Weight-Related Factors Tied to Outcomes of Chronic Hepatitis C
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- Head-to-Head Trial Finds HCV Regimens Equal
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- Interferon and Ribavirin Second-Line Option for Hepatitis C
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- DDW: Interferon Has Long-Term Histo Benefits in HCV
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- FDA May Restrict Acetaminophen
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- Detectable HCV RNA at Week 8 Is Best Predictor of Relapse in Genotype 1
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- DDW: Telaprevir Improves HCV Clearance in Resistant Patients
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- Hypothyroidism In Women Associated With Liver Cancer
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- Sustained Response Seen with New Hepatitis C Drug
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- Re-treatment of Chronic Hepatitis C Patients Who Do Not Respond to Pegylated Interferon Alfa-2b (PegIntron)
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- Promising Promising Early Results from the First Clinical Trial of a Combination Regimen of 2 Oral Antiviral Agents for Chronic Hepatitis C
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- Necessities of Interferon Therapy in Elderly Patients with Chronic Hepatitis C
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- HCV Vaccine Development
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- Pegylated Interferon alfa-2a (Pegasys) Relapse Rates in Genotype 1 Chronic Hepatitis C Patients Depend on Weight-based Ribavirin Dosage
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- Overview of the Current Standard of Care for Treatment of Chronic Hepatitis C
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- Response To Therapy In Chronic Hepatitis C Predicted By 2-Day Results
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- Vertex Acquires VCH-222 and VCH-759, Two Experimental Oral HCV Polymerase Inhibitors
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- Hepatitis C Linked to Increased Risk of Intrahepatic Cholangiocarcinoma
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- Liver Biopsies Indicate Persistent Inflammation and Fibrosis in HCV Antibody Positive People with Undetectable HCV RNA
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- Pharmasset and Roche Obtain FDA Consent to Start a Phase 2b Study with R7128 in Treatment Naive HCV Patients
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- Human Genome Sciences Announces Initiation of Phase 2b Trial 0f Albuferon Dosed Monthly in Chronic Hepatitis C
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- Although Hepatitis C Treatment Reduces The Virus, Liver Damage Continues
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- Human Genome Sciences Announces Albuferon(R) Meets Primary Endpoint In Phase 3 Trial In Chronic Hepatitis C
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- Pegylated interferon alpha2a is more effective in some hepatitis C patients with specific genotypes than the alpha2b form of the drug, an Italian researcher said
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- HCV Polymerase Inhibitor R7128 Demonstrates Good Antiviral Activity in Genotype 2 or 3 Prior Non-responders and Relapsers
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- Hepatitis C patients may have abnormal blood sugar
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- FDA Approves Nexavar for Patients with Inoperable Liver Cancer
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- Sustained Virological Response to Pegylated Interferon Alfa-2b (PegIntron) with or without Ribavirin Predicts Continued Response through 5 Years
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- Symptoms and Response to Interferon plus Ribavirin in Children with Chronic Hepatitis C
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- Safety and Activity of Once-Monthly Albinterferon Alfa-2b (Albuferon) in Genotype 2/3 Chronic Hepatitis C Patients
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- Insulin Resistance Independently Associated With Chronic Hepatitis C
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- Pathology of Chronic Hepatitis C in Children: Peds-C Trial
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- Silymarin (Milk Thistle) Does Not Affect Hepatitis C Virus Activity or ALT Levels in HCV Patients, but Users Report Fewer Symptoms and Better Quality of Life than Non Users
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- Acute Hepatitis C Infection and Spontaneous Viral Clearance in Adults and Children
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- How Effective Is Pegylated Interferon plus Ribavirin for HCV Genotype 1 Patients Over Age 50?
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- Depression Due to Treatment with Pegylated Interferon plus Ribavirin May Be Under-diagnosed by Clinicians
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- HALT-C Trial Shows Minimal Long-term Benefit of Pegylated Interferon Alfa-2a (Pegasys) Maintenance Therapy in Patients with Chronic Hepatitis C
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- Use of Epoetin (EPO) to Manage Anemia in Chronic Hepatitis C Patients Treated with Pegylated Interferon plus Ribavirin
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- Incidence and Predictors of Hepatocellular Carcinoma in Patients With Cirrhosis
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- HCV Care by Liver Specialists or Community-Based Practices: Pro & Con
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- Decreased HCV-specific Immunity in African-Americans May Help Explain Poorer Response to Antiviral Therapy
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- 400,000 IU/mL Is the Optimal Baseline Viral Load Cut-off to Predict Response In Treatment-naive Patients with Genotype 1 HCV
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- Liver Stiffness Predicts Portal Hypertension in HCV Cirrhosis
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- EASL: Sustained Virologic Response Equals Cure for HCV Infection
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- Racial Differences Seen In Steatosis In Patients With Hepatitis C
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- New Vaccine Schedule Offers Protection Against Hepatitis A And Hepatitis B
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- Interferon Gamma Does Not Reverse Fibrosis in Hepatitis C Patients with Advanced Liver Disease
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- Hepatitis C in African Americans
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- Three Studies Examine Syringe Exchange Policies in the U.S.
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- Short-course Pegylated Interferon for Acute Hepatitis C
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- Heavy-Drinking Women with HCV Infection Cut Decade Off Life
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- Treatment Response in Cirrhotic Hepatitis C Patients with Portal Hypertension
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- Integrating Medical and Mental Health Care Improves Likelihood of Initiation and Adherence to Hepatitis C Treatment
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- Rapid Decline of HCV RNA in Patients Treated with VX-950
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- Predicting Survival After Liver Transplant
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- Patients Who Recover from Hepatitis C Have Lower Risk of Reinfection
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- New Therapy Significantly Increases Platelet Count
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- Is Hepatitis A and B Screening and Vaccination in Chronic Hepatitis C Patients Effective?
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- Sustained Virological Response to PegIntron Plus Ribavirin in Asian and Hispanic Patients
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